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Cat Health:
Vaccine-Related Tumors

 

Lately, much controversy concerning  vaccination and over-vaccination has been in the news.  This has been due to a fairly recent discovery relating vaccine administration in cats to subsequent occurrence of tumor at the site of the vaccination. 

The incidence of occurrence of tumors in cats from vaccine is low; less than 5 percent of the cat population vaccinated develop tumor at the site of vaccination. 

The tumor known as Fibrosarcoma, is a malignant tumor, meaning it grows uncontrollably and spreads fairly rapidly.  Usually, this tumor does not metastasize, meaning that it does not spread to distant sites from its original location.  However, it is very aggressive locally, and unless caught early, and surgically removed completely, regrowth will occur with a vengeance.

It is now thought that the part of the vaccine which acts to promote the affect of the virus being vaccinated for, known as the adjuvant, may be the cause of tumor formation.  Still much controversy and study into this matter is underway, trying to determine if one cause or more than one cause for the tumor formation exists.

Cats appear to be the only species to date affected by this abnormal tumor reaction from vaccination; none has yet to be reported to occur in other species.

Two vaccines have been implicated in the cause of fibrosarcoma formation in the cat: the leukemia virus vaccine, and the rabies vaccine.  Some vaccine manufacturers have developed rabies vaccine which will create immunity over a 3 year period.  This decreases then the annual frequency of vaccine administration for the rabies vaccine, thus decreasing the chance of tumor formation by reducing the frequency of vaccination. 

Cats who normally are inside only, with little contact with outdoors or patios, and no contact with other cats even through screen enclosures, are usually protected from feline leukemia and rabies viruses.  However, by law in most states, rabies vaccine must be administered to all pets in a household. 

Recently, a vaccine known as Purevax has been manufactured for rabies which contains no adjuvant.  Frequency of administration is annually, yet the risk of vaccine induced tumor from an adjuvant has been removed. 

Check with your veterinarian, or submit your request to Questions for the vet to determine what may be the best recommendation for vaccination protocol for your pet.