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Grape and raisin toxicity

 

Long regarded as healthy treats for our pets, both grapes and raisins have been associated with toxic properties and associated deaths in dogs who have ingested various amounts of grapes or raisins. Although it is still uncertain as to what is/are the toxic ingredient(s) in grapes and raisins, it is now clear that they are far from healthy for our pets.

Around 1999, Animal Poison Control Center (APCC) began to notice a trend in dogs who had eaten grapes or raisins. Nearly all developed acute renal (kidney) failure. Ingested grapes were either purchased fresh from grocery stores or grown in private yards, and were of various brand names. Ingested amounts varied as well; from over a pound of grapes to as little as a single serving of raisins.

APCC's data base showed that dogs who ate the grapes and raisins typically vomited within a few hours of ingestion. Vomitous revealed partially digested grapes or raisins. At this point, some dogs stopped eating, developed diarrhea, and became quiet and lethargic, showing signs of abdominal pain. Symptoms lasted for several days to weeks.

Abnormalities in kidney function tests were evident anywhere from 24 hours to several days after the dogs ate the fruit. As the kidney damage developed , the dogs would produce little urine. When they could no longer produce urine, death occurred.

Why the fruit causes dogs to become ill no one knows. Suspect grapes and raisins have been checked for pesticides, heavy metals (such as lead and zinc), mycotoxins (fungal contaminants), and so far all have come back negative.

Although the exact cause of the renal failure is unknown, treatment can be successful. Recent ingestion cases can be induced to vomit, and given activated charcoal to absorb potential toxins. Dogs should be hospitalized and placed on fluids for at least 48 hours. Blood tests are monitored for the effects on the kidney function tests. Treatment is maintained until function tests have normalized.